5-(2-Fluoro-phenoxy)-2-pyridin-2-yl-6-(6-ethanesulfonyl-pyridin-3-yloxy)-1H-benzimidazole → HCID 178477649, 화합물

HRID 13311

반응식

HRID 13311 반응식
[F:1][C:2]1[CH:35]=[CH:34][CH:33]=[CH:32][C:3]=1[O:4][C:5]1[C:19]([O:20][C:21]2[CH:22]=[N:23][C:24]([S:27]([CH2:30][CH3:31])(=[O:29])=[O:28])=[CH:25][CH:26]=2)=[CH:18][C:8]2[NH:9][C:10]([C:12]3[CH:17]=[CH:16]C=C[N:13]=3)=[N:11][C:7]=2[CH:6]=1.[NH:36]1C=CC(C=O)=N1>>[F:1][C:2]1[CH:35]=[CH:34][CH:33]=[CH:32][C:3]=1[O:4][C:5]1[C:19]([O:20][C:21]2[CH:22]=[N:23][C:24]([S:27]([CH2:30][CH3:31])(=[O:28])=[O:29])=[CH:25][CH:26]=2)=[CH:18][C:8]2[NH:9][C:10]([C:12]3[CH:17]=[CH:16][NH:36][N:13]=3)=[N:11][C:7]=2[CH:6]=1

참가 물질

3

반응물 2

HCID 113977045-(2-Fluoro-phenoxy)-2-pyridin-2-yl-6-(6-ethanesulfonyl-pyridin-3-yloxy)-1H-benzimidazoleHCID 122183831H-Pyrazole-3-carbaldehyde

생성물 1

HCID 178477649HCID 178477649, 화합물

실험 절차

The entitled compound was obtained as a pale yellow solid in the same method as in Example 202 or in accordance with the method or by combining it with an ordinary method but using 4-(2-fluoro-phenoxy)-5-(6-ethanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 223 and 1H-pyrazole-3-carboxaldehyde.

후처리

  1. customThe entitled compound was obtained as a pale yellow solid in the same method as in Example 202 or in accordance with the method

출처 및 근거

ORD 기록
ord-3ed65b1bc704456483d2b246cc14d0d4
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07728025B2

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