Acetic Acid → Methyl 4-(2-acetylhydrazino)benzoate

HRID 133174

반응식

HRID 133174 반응식
[NH:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1)[NH2:2].[CH3:13][C:14](O)=[O:15]>C([O-])(=O)C.[Na+]>[C:14]([NH:2][NH:1][C:3]1[CH:4]=[CH:5][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:11][CH:12]=1)(=[O:15])[CH3:13]

참가 물질

4

반응물 2

HCID 176Acetic AcidHCID 408928Methyl 4-hydrazinylbenzoate

생성물 1

HCID 12765612Methyl 4-(2-acetylhydrazino)benzoate수율 115.7%

시약·촉매·용매 1

HCID 517045Sodium Acetate용매

반응 조건

온도
80 °C

실험 절차

5.5 g of methyl 4-hydrazinobenzoate are dissolved in 38.2 ml of AcOH comprising 2.4 g of sodium acetate and the mixture is heated at 80° C. for 18 hours. The inorganic material is filtered off, the filtrate is then evaporated and the residue is taken up in the minimum amount of Et2O. The mixture is filtered to produce 7.97 g of the expected compound.

후처리

  1. filtrationThe inorganic material is filtered off
  2. customthe filtrate is then evaporated
  3. filtrationThe mixture is filtered

출처 및 근거

ORD 기록
ord-07f58774b4744ce2b08cb56ac6cf1c96
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07390818B2

연결된 노트

불러오는 중…