Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl 3-Hydroxyphenylacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 3'-Hydroxyphenylacetic acid | HCID 12122 | — |
| 용매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | Methyl 3-Hydroxyphenylacetate | HCID 39129 | — |
반응 단계
10 g of 3-hydroxyphenylacetic acid are dissolved in 60 ml of methanol and 2.5 ml of sulphuric acid. The solution is heated at reflux for two hours. It is brought back to ambient temperature and the methanol is evaporated. The residue is taken up in a saturated K2CO3 solution. Extraction is carried out with AcOEt. The organic phase is dried over MgSO4, filtered and evaporated to dryness. 11.1 g of oil are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07390818B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-7422c6e426094c6b92808842d39c97dd |
| 출처 메모 | uspto-grants-2008_06 |