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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 13322생성일: 2026년 10월 25일

1-methyl-1H-pyrazole-3-carboxylic acid → 5-(2-Difluoromethoxy-pyridin-3-yloxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-(1-methyl-1H-pyrazol-3-yl)-1H-benzimidazole

https://huagongshe.com/reaction/13322

반응식

참여 물질

역할이름HCID투입량
반응물1-methyl-1H-pyrazole-3-carboxylic acidHCID 573176—
반응물5-(2-Difluoromethoxy-pyridin-3-yloxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-pyridin-2-yl-1H-benzimidazoleHCID 11489567—
생성물5-(2-Difluoromethoxy-pyridin-3-yloxy)-6-(6-ethanesulfonyl-pyridin-3-yloxy)-2-(1-methyl-1H-pyrazol-3-yl)-1H-benzimidazoleHCID 135697962—

반응 단계

The entitled compound was obtained as a colorless solid in the same method as in Example 203 or in accordance with the method or by combining it with an ordinary method but using 4-(2-difluoromethoxy-pyridin-3-yloxy)-5-(6-ethanesulfonyl-pyridin-3-yloxy)-benzene-1,2-diamine obtained in Example 247 and 1-methyl-1H-pyrazole-3-carboxylic acid.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07728025B2
출처 데이터셋uspto-grants-2010_06
ORD IDord-432da6b11ae548539f0b1457a1ae19c0
출처 메모uspto-grants-2010_06