Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(3,4-dichlorophenyl)alanine → 3-(N'-(3,4-Dichlorophenyl)-D,L-alaninyl)amino-epsilon-caprolactam
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(3,4-dichlorophenyl)alanine | HCID 5491659 | — |
| 반응물 | (S)-4-Aminoazepan-2-one | HCID 18603542 | — |
| 생성물 | 3-(N'-(3,4-Dichlorophenyl)-D,L-alaninyl)amino-epsilon-caprolactam | HCID 69268404 | — |
반응 단계
Following General Procedure A above using N-(3,4-dichlorophenyl)-D,L-alanine (Example Q) and 3-(S)-amino-ε-caprolactam (Sigma), the title compound was prepared as a solid having a melting point of 199° C. The reaction was monitored by tlc on silica gel (Rf=0.4 in 50% ethyl acetate/hexanes) and purification was by preparative thin layer chromatography using 50% ethyl acetate/hexanes as the eluant.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07390801B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-3675621d0d3d45eaaf9c74b1c78b1d9d |
| 출처 메모 | uspto-grants-2008_06 |