반응식
[F:1][C:2]1[CH:24]=[CH:23][CH:22]=[CH:21][C:3]=1[O:4][C:5]1[C:19]([OH:20])=[CH:18][C:8]2[NH:9][C:10]([C:12]3[CH:17]=[N:16][CH:15]=[CH:14][N:13]=3)=[N:11][C:7]=2[CH:6]=1.Br[C:26]1[CH:27]=[CH:28][C:29]([C:32]#[N:33])=[N:30][CH:31]=1>>[F:1][C:2]1[CH:24]=[CH:23][CH:22]=[CH:21][C:3]=1[O:4][C:5]1[C:19]([O:20][C:26]2[CH:31]=[N:30][C:29]([C:32]#[N:33])=[CH:28][CH:27]=2)=[CH:18][C:8]2[NH:9][C:10]([C:12]3[CH:17]=[N:16][CH:15]=[CH:14][N:13]=3)=[N:11][C:7]=2[CH:6]=1참가 물질
3
실험 절차
The entitled compound was obtained as a yellow solid in the same method as in Example 251 (step 2) or in accordance with the method or by combining it with an ordinary method but using 5-(2-fluorophenoxy)-6-hydroxy-2-pyrazin-2-yl-1H-benzimidazole obtained in Example 251 (step 1) and 5-bromo-2-cyanopyridine.
후처리
- customThe entitled compound was obtained as a yellow solid in the same method as in Example 251 (step 2) or in accordance with the method
출처 및 근거
- ORD 기록
- ord-badeeb24b3bb487ca7ac18271e18a665
- 출처 데이터셋
- uspto-grants-2010_06
- 특허 번호
- US07728025B2
연결된 노트
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