Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 3,5-Dichlorobenzyl methanesulfonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Methanesulfonyl chloride | HCID 31297 | — |
| 반응물 | 3,5-Dichlorobenzylic alcohol | HCID 43236 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3,5-Dichlorobenzyl methanesulfonate | HCID 22492253 | — |
반응 단계
To a solution of 3.5 g of 3,5-dichlorobenzyl alcohol (Aldrich) in 75 mL of dichloromethane at 0° C. was added 1.8 mL of methane sulfonylchloride followed by 3.5 mL of triethylamine added dropwise. After 2 hours the solution was diluted to 150 mL with dichloromethane, washed with 3N HCl, saturated aqueous NaHCO3 dried with Na2SO4 and the solvents removed to yield the desired 3,5-dichlorobenzyl methanesulfonate as a yellow oil that was used without purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07390801B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-82ce7505cc384f4c9ec0c6e9a0874efc |
| 출처 메모 | uspto-grants-2008_06 |