3-Pyridinol, 2-(difluoromethoxy)- → 5-(2-Difluoromethoxy-pyridin-3-yloxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole
반응식
C(OC(C1C=[CH:37][CH:36]=[CH:35][C:7]=1[O:8][C:9]1[C:23]([O:24][C:25]2[CH:30]=[CH:29][C:28]([S:31]([CH3:34])(=[O:33])=[O:32])=[CH:27][CH:26]=2)=[CH:22][C:12]2[NH:13][C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)=[N:15][C:11]=2[CH:10]=1)=O)C.[F:39][CH:40]([F:49])[O:41][C:42]1C(O)=CC=C[N:43]=1>>[F:39][CH:40]([F:49])[O:41][C:42]1[C:7]([O:8][C:9]2[C:23]([O:24][C:25]3[CH:26]=[CH:27][C:28]([S:31]([CH3:34])(=[O:32])=[O:33])=[CH:29][CH:30]=3)=[CH:22][C:12]3[NH:13][C:14]([C:16]4[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=4)=[N:15][C:11]=3[CH:10]=2)=[CH:35][CH:36]=[CH:37][N:43]=1참가 물질
3
실험 절차
The entitled compound was obtained as a pale yellow solid in the same method as in Example 14 or in accordance with the method or by combining it with an ordinary method but using 5-fluoro-4-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14 and 2-difluoromethoxy-pyridin-3-ol.
후처리
- customThe entitled compound was obtained as a pale yellow solid in the same method as in Example 14 or in accordance with the method