3-Nitrophenylacetic acid → 2-[(3Nitrophenyl)acetamido]butyric acid iso-butyl ester

HRID 133366

반응식

HRID 133366 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([CH2:10][C:11]([OH:13])=O)[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].[NH2:14][CH:15]([CH2:23][CH3:24])[C:16]([O:18][CH2:19][CH:20]([CH3:22])[CH3:21])=[O:17]>>[CH2:19]([O:18][C:16](=[O:17])[CH:15]([NH:14][C:11](=[O:13])[CH2:10][C:6]1[CH:7]=[CH:8][CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1)[CH2:23][CH3:24])[CH:20]([CH3:21])[CH3:22]

참가 물질

3

반응물 2

HCID 158763-Nitrophenylacetic acidHCID 13743360Isobutyl 2-aminobutyrate

생성물 1

HCID 539659122-[(3Nitrophenyl)acetamido]butyric acid iso-butyl ester

실험 절차

Following General Procedure BI above and using 3-nitrophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

후처리

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

출처 및 근거

ORD 기록
ord-a64bd1ea7e354849b501212b815bbf40
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07390801B2

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