2,4-Dichlorophenylacetic acid → 2-[(2,4-Dichlorophenyl)acetamido]butyric acid isobutyl ester

반응식

[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10]([OH:12])=O.[NH2:13][CH:14]([CH2:22][CH3:23])[C:15]([O:17][CH2:18][CH:19]([CH3:21])[CH3:20])=[O:16]>>[CH2:18]([O:17][C:15](=[O:16])[CH:14]([NH:13][C:10](=[O:12])[CH2:9][C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[Cl:1])[CH2:22][CH3:23])[CH:19]([CH3:20])[CH3:21]

참가 물질

반응물 2

HCID 882092,4-Dichlorophenylacetic acid

HCID 13743360Isobutyl 2-aminobutyrate

생성물 1

HCID 541261332-[(2,4-Dichlorophenyl)acetamido]butyric acid isobutyl ester

실험 절차

Following General Procedure BI above and using 2,4-dichlorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

후처리

customThe reaction was monitored by tlc on silica gel and purification
filtrationwas by filtration

출처 및 근거

ORD 기록: ord-cf2c25ce90db4dec8ac08fbf5d7839ed
출처 데이터셋: uspto-grants-2008_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07390801B2

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