1-Methyl-3-hydroxypyridine-2-one → 5-(1-Methyl-2-oxo-1,2-dihydro-pyridin-3-yloxy)-6-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-1H-benzimidazole
반응식
C(OC([C:6]1[CH:38]=[CH:37]C=C[C:7]=1[O:8][C:9]1[C:23]([O:24][C:25]2[CH:30]=[CH:29][C:28]([S:31]([CH3:34])(=[O:33])=[O:32])=[CH:27][CH:26]=2)=[CH:22][C:12]2[NH:13][C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)=[N:15][C:11]=2[CH:10]=1)=O)C.[CH3:39][N:40]1C=CC=C(O)[C:41]1=[O:47]>>[CH3:39][N:40]1[CH:37]=[CH:38][CH:6]=[C:7]([O:8][C:9]2[C:23]([O:24][C:25]3[CH:26]=[CH:27][C:28]([S:31]([CH3:34])(=[O:33])=[O:32])=[CH:29][CH:30]=3)=[CH:22][C:12]3[NH:13][C:14]([C:16]4[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=4)=[N:15][C:11]=3[CH:10]=2)[C:41]1=[O:47]참가 물질
3
실험 절차
The entitled compound was obtained as a brown solid in the same method as in Example 14 or in accordance with the method or by combining it with an ordinary method but using 5-fluoro-4-(4-methanesulfonyl-phenoxy)-2-nitro-phenylamine obtained in Example 14 and 1-methyl-2-oxo-1,2-dihydro-pyridin-3-ol.
후처리
- customThe entitled compound was obtained as a brown solid in the same method as in Example 14 or in accordance with the method