3-(Methylthio)phenylacetic acid → N-[(3-methylthiophenyl)acetyl]alanine Iso-butyl Ester

HRID 133381노트

반응식

HRID 133381 반응식
[CH3:1][S:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]([OH:12])=O)[CH:6]=[CH:7][CH:8]=1.[CH2:13]([O:17][C:18](=[O:22])[C@H:19]([CH3:21])[NH2:20])[CH:14]([CH3:16])[CH3:15]>>[CH2:13]([O:17][C:18](=[O:22])[C@H:19]([CH3:21])[NH:20][C:10](=[O:12])[CH2:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([S:2][CH3:1])[CH:4]=1)[CH:14]([CH3:16])[CH3:15]

참가 물질

3

반응물 2

HCID 27374613-(Methylthio)phenylacetic acidHCID 137435562-methylpropyl (2S)-2-aminopropanoate

생성물 1

HCID 15481777N-[(3-methylthiophenyl)acetyl]alanine Iso-butyl Ester

실험 절차

Following General Procedure BI above, and using 3-methylthiophenylacetic acid (CAS#18698-73-2) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

후처리

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

출처 및 근거

ORD 기록
ord-283b2766d72e4a86a91fb7e1564e57c0
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07390801B2

반응 노트

불러오는 중…