p-Tolylacetic acid → N-[(4-methylphenyl)acetyl]alanine iso-butyl ester

HRID 133388

반응식

HRID 133388 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.[CH2:12]([O:16][C:17](=[O:21])[C@H:18]([CH3:20])[NH2:19])[CH:13]([CH3:15])[CH3:14]>>[CH2:12]([O:16][C:17](=[O:21])[C@H:18]([CH3:20])[NH:19][C:9](=[O:11])[CH2:8][C:5]1[CH:4]=[CH:3][C:2]([CH3:1])=[CH:7][CH:6]=1)[CH:13]([CH3:15])[CH3:14]

참가 물질

3

반응물 2

HCID 248474p-Tolylacetic acidHCID 137435562-methylpropyl (2S)-2-aminopropanoate

생성물 1

HCID 53936136N-[(4-methylphenyl)acetyl]alanine iso-butyl ester

실험 절차

Following General Procedure BI above, and using 4-methylphenylacetic acid (Aldrich) and L-alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

후처리

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

출처 및 근거

ORD 기록
ord-5a43e2084ae9449099f61de5cfe9e39f
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07390801B2

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