2,3-Difluorobenzonitrile → 3-Fluoro-4-(2-fluoro-6-cyano-phenoxy)-phenylamine

HRID 13376

반응식

HRID 13376 반응식
[F:1][C:2]1[CH:3]=[C:4]([NH:9]C(=O)OC(C)(C)C)[CH:5]=[CH:6][C:7]=1[OH:8].[F:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([C:24]#[N:25])[C:19]=1F>>[F:1][C:2]1[CH:3]=[C:4]([NH2:9])[CH:5]=[CH:6][C:7]=1[O:8][C:19]1[C:20]([C:24]#[N:25])=[CH:21][CH:22]=[CH:23][C:18]=1[F:17]

참가 물질

3

실험 절차

The entitled compound was obtained in the same method as in Example 221 (step 1) or in accordance with the method or by combining it with an ordinary method but using tert-butyl (3-fluoro-4-hydroxy-phenyl)-carbamate obtained in Example 196 (step 1) and 1,2-difluoro-3-cyano-benzene.

후처리

  1. customThe entitled compound was obtained in the same method as in Example 221 (step 1) or in accordance with the method

출처 및 근거

ORD 기록
ord-414d8a4d43ff49a59592db1cbfed2ad3
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07728025B2

연결된 노트

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