Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Methylsulfonyl)phenol → 1-acetyl-2-(5-(4-(methanesulfonyl)phenoxy)-2-pyridin-2-yl-1H-benzimidazol-6-yl)pyrrolidin-3-yl acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Methylsulfonyl)phenol | HCID 123350 | — |
| 반응물 | 1-Acetyl-2-(2-fluoro-5-nitro-4-((pyridin-2-ylcarbonyl)amino)phenyl)pyrrolidin-3-yl acetate | HCID 67483074 | — |
| 생성물 | 1-acetyl-2-(5-(4-(methanesulfonyl)phenoxy)-2-pyridin-2-yl-1H-benzimidazol-6-yl)pyrrolidin-3-yl acetate | HCID 67482257 | — |
반응 단계
The entitled compound was obtained as a white solid in the same method as in Example 338 (step 5) or in accordance with the method or by combining it with an ordinary method but using 4-(methanesulfonyl)phenol and (1-acetyl-2-(2-fluoro-5-nitro-4-((pyridin-2-ylcarbonyl)amino)phenyl)pyrrolidin-3-yl acetate diastereomer A.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728025B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-07de9e32f5b2442db95aef7c86370ae0 |
| 출처 메모 | uspto-grants-2010_06 |