HCID 23145445, 화합물 → HCID 11329193, 화합물

HRID 13415노트

반응식

HRID 13415 반응식
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:12][CH2:11][O:10][C:9]2=[O:13])=[CH:4][CH:3]=1.[C:14]([N:17]1[CH2:21][CH2:20][CH2:19][CH:18]1[C:22]1[C:27](F)=[CH:26][C:25]([NH:29][C:30]([C:32]2[CH:37]=[N:36][CH:35]=[CH:34][N:33]=2)=O)=[C:24]([N+:38]([O-])=O)[CH:23]=1)(=[O:16])[CH3:15]>>[C:14]([N:17]1[CH2:21][CH2:20][CH2:19][CH:18]1[C:22]1[C:27]([O:1][C:2]2[CH:3]=[CH:4][C:5]([N:8]3[CH2:12][CH2:11][O:10][C:9]3=[O:13])=[CH:6][CH:7]=2)=[CH:26][C:25]2[N:29]=[C:30]([C:32]3[CH:37]=[N:36][CH:35]=[CH:34][N:33]=3)[NH:38][C:24]=2[CH:23]=1)(=[O:16])[CH3:15]

참가 물질

3

반응물 2

HCID 23145445HCID 23145445, 화합물HCID 231456783-(4-Hydroxyphenyl)-1,3-oxazolidin-2-one

생성물 1

HCID 11329193HCID 11329193, 화합물

실험 절차

The entitled compound was obtained as a yellow oily substance in the same method as in Example 338 (step 5) or in accordance with the method or by combining it with an ordinary method but using 3-(4-hydroxyphenyl)-1,3-oxazolidin-2-one and N-(4-(1-acetylpyrrolidin-2-yl)-5-fluoro-2-nitrophenyl)pyrazin-2-carboxamide enantiomer B obtained in Example 569 (step 5).

후처리

  1. customThe entitled compound was obtained as a yellow oily substance in the same method as in Example 338 (step 5) or in accordance with the method
  2. customobtained in Example 569 (step 5)

출처 및 근거

ORD 기록
ord-04835c708778486ab90df4b1a9cec871
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07728025B2

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