Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methyl-5-hydroxypyridine → 6-(1-Acetyl-5-methylpyrrolidin-2-yl)-5-((6-methylpyridin-3-yl)oxy)-2-pyridin-2-yl-1H-benzimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methyl-5-hydroxypyridine | HCID 14275 | — |
| 반응물 | N-(4-(1-acetyl-5-methylpyrrolidin-2-yl)-5-fluoro-2-nitrophenyl)pyridine-2-carboxamide | HCID 23145552 | — |
| 생성물 | 6-(1-Acetyl-5-methylpyrrolidin-2-yl)-5-((6-methylpyridin-3-yl)oxy)-2-pyridin-2-yl-1H-benzimidazole | HCID 23145192 | — |
반응 단계
The entitled compound was obtained as a pale yellow solid in the same method as in Example 338 (step 5) or in accordance with the method or by combining it with an ordinary method but using N-(4-(1-acetyl-5-methylpyrrolidin-2-yl)-5-fluoro-2-nitrophenyl)pyridine-2-carboxamide obtained in Example 545 and 6-methylpyridin-3-ol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728025B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-e9a8116868f6419094ed6c0955c19366 |
| 출처 메모 | uspto-grants-2010_06 |