N-[4-(5-oxo-3,4-dihydro-2H-1-benzazepine-1-carbonyl)phenyl]-2-phenylbenzamide → HCID 19694863, 화합물
반응식
[C:1]1([C:7]2[CH:35]=[CH:34][CH:33]=[CH:32][C:8]=2[C:9]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([N:20]3[C:26]4[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=4[C:24](=O)[CH2:23][CH2:22][CH2:21]3)=[O:19])=[CH:14][CH:13]=2)=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:36].[N:37]1[CH:42]=[CH:41][CH:40]=[C:39]([CH2:43][C:44]([NH2:46])=[S:45])[CH:38]=1>>[ClH:36].[N:37]1[CH:42]=[CH:41][CH:40]=[C:39]([CH2:43][C:44]2[S:45][C:23]3[CH2:22][CH2:21][N:20]([C:18]([C:15]4[CH:16]=[CH:17][C:12]([NH:11][C:9](=[O:10])[C:8]5[CH:32]=[CH:33][CH:34]=[CH:35][C:7]=5[C:1]5[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=5)=[CH:13][CH:14]=4)=[O:19])[C:26]4[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=4[C:24]=3[N:46]=2)[CH:38]=1참가 물질
3
실험 절차
Using 400 mg of 2-phenyl-4'-[(5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]benzanilide and 400 mg of 3-pyridylthioacetamide hydrochloride, the procedure of Example 5 was repeated to obtain 100 mg of 4'-[[2-(3-pyridylmethyl)-5,6-dihydro-4H-thiazolo[5,4-d][1]benzazepin-6-yl)carbonyl]-2-phenylbenzanilide hydrochloride as an amorphous solid.
출처 및 근거
- ORD 기록
- ord-90050701c8ef48ae805729e1fea02e48
- 출처 데이터셋
- uspto-grants-1998_03