Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Bromoaniline → (4-Bromophenyl)(5-methoxybenzoxazol-2-yl)amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Bromoaniline | HCID 7807 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | 2-Chloro-5-methoxy-1,3-benzoxazole | HCID 11819712 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | (4-Bromophenyl)(5-methoxybenzoxazol-2-yl)amine | HCID 22040817 | — |
반응 단계
The mixture containing 2-chloro-5-methoxybenzoxazole (1 eq), 4-bromoaniline (2 eq) and diisopropylethylamine was refluxed in dimethylformamide. The resultant mixture was concentrated and partitioned between ethyl acetate and water. The organic layer was washed with brine and dried. Purification on silica gel gave (4-bromophenyl)(5-methoxybenzoxazol-2-yl)amine. MS: MH+=318
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728010B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-9bac4797f8dc4d1cae695a5979e23f2d |
| 출처 메모 | uspto-grants-2010_06 |