Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Nitroacetophenone → HCID 10999672, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Nitroacetophenone | HCID 7487 | — |
| 반응물 | Benzylamine | HCID 7504 | — |
| 반응물 | Sodium triacetoxyborohydride | HCID 5049666 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | HCID 10999672 | HCID 10999672 | — |
반응 단계
To a solution of 1-(4-nitrophenyl)ethan-1-one (1 eq) and phenylmethylamine (1 eq) in methanol was added sodium triacetoxyborohydride (1.2 eq). The resulting mixture was stirred at ambient temperature for 16 h. The mixture was concentrated and partitioned between ethyl acetate and water. The organic layer was concentrated and preparative purification yielded [(4-nitrophenyl)ethyl]benzylamine. MS: MH+=256.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07728010B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-e35429549cc24636b5bc31c27c701b89 |
| 출처 메모 | uspto-grants-2010_06 |