6-benzyl-7-dibenzylamino-2-fluoro-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one → HCID 73741654, 화합물
반응식
[CH2:1]([CH:8]1[CH:14]([N:15](CC2C=CC=CC=2)CC2C=CC=CC=2)[C:13](=[O:30])[NH:12][C:11]2[CH:31]=[C:32]([F:35])[CH:33]=[CH:34][C:10]=2[O:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CO.[Pd]>[NH2:15][CH:14]1[C:13](=[O:30])[NH:12][C:11]2[CH:31]=[C:32]([F:35])[CH:33]=[CH:34][C:10]=2[O:9][CH:8]1[CH2:1][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1참가 물질
4
실험 절차
The title compound was prepared by hydrogenation of (−)-(6S,7S or 6R,7R)-6-benzyl-7-dibenzylamino-2-fluoro-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one in methanol with Pd/C (10%), MS m/e (%): 287.1 (M+H+, 100).
출처 및 근거
- ORD 기록
- ord-6921dc229b29408b8409ea8a9d530447
- 출처 데이터셋
- uspto-grants-2007_05
- 특허 번호
- US07211573B2
반응 노트
불러오는 중…