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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1348709생성일: 2026년 10월 26일

tert-Butyl piperazine-1-carboxylate → 4-(4-tert-butoxycarbonyl-1-piperazinyl)methyl-6-(3-fluoro-4-methoxyphenyl)-2-isobutyl-2H-pyridazin-3-one

https://huagongshe.com/reaction/1348709

반응식

참여 물질

역할이름HCID투입량
반응물tert-Butyl piperazine-1-carboxylateHCID 143452—
반응물6-(3-fluoro-4-methoxyphenyl)-2-isobutyl-4-methanesulfonyloxymethyl-2H-pyridazin-3-oneHCID 86605972—
생성물4-(4-tert-butoxycarbonyl-1-piperazinyl)methyl-6-(3-fluoro-4-methoxyphenyl)-2-isobutyl-2H-pyridazin-3-oneHCID 2199160994.3%

반응 단계

Following the procedure of Example 1(10), 6-(3-fluoro-4-methoxyphenyl)-2-isobutyl-4-methanesulfonyloxymethyl-2H-pyridazin-3-one and tert-butyl 1-piperazinecarboxylate were reacted to yield the title compound as a yellow oil (yield: 94.3%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07211577B2
출처 데이터셋uspto-grants-2007_05
ORD IDord-e6372f18395847699ee2c9bbded66364
출처 메모uspto-grants-2007_05