5-Benzoyl-4-phenyl-1,3-thiazole-2-sulfonyl chloride → HCID 21092802, 화합물
반응식
Cl.Cl.[CH2:3]([O:5][C:6](=[O:12])[CH2:7][NH:8][CH2:9][CH2:10][NH2:11])[CH3:4].[C:13]([C:21]1[S:25][C:24]([S:26](Cl)(=[O:28])=[O:27])=[N:23][C:22]=1[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:3]([O:5][C:6](=[O:12])[CH2:7][NH:8][CH2:9][CH2:10][NH:11][S:26]([C:24]1[S:25][C:21]([C:13](=[O:20])[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)=[C:22]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[N:23]=1)(=[O:27])=[O:28])[CH3:4]참가 물질
3
실험 절차
The title compound was synthesized by the reaction of N-(2-aminoethyl)-glycine ethyl ester 2HCl with 5-benzoyl-4-phenyl-thiazole-2-sulfonyl chloride as per the procedure of example 1. 1H NMR (500 MHz; DMSO-d6) δ 7.46 (d, 2H), 7.36–7.24 (m, 4H), 7.19–7.11 (m, 4H), 4.05 (q, 2H), 3.28 (s, 2H), 3.19 (t, 2H), 2.66 (t, 2H), 1.16 (t, 3H).
출처 및 근거
- ORD 기록
- ord-787f98f0085a4656ae516c36c3497444
- 출처 데이터셋
- uspto-grants-2007_05
- 특허 번호
- US07211668B2