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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1349070생성일: 2026년 10월 26일

2,1,3-Benzothiadiazol-4-amine → (2S,4EZ)-N-(2,1,3-benzothiadiazol-4-yl)-4-(cyanomethylene)-1-(diphenylacetyl)-2-pyrrolidinecarboxamide

https://huagongshe.com/reaction/1349070

반응식

참여 물질

역할이름HCID투입량
반응물2,1,3-Benzothiadiazol-4-amineHCID 69845—
반응물2,2-Diphenylacetyl chlorideHCID 74637—
반응물(2S,4EZ)-1-(tertbutoxycarbonyl)-4-(cyanomethylene)-2-pyrrolidinecarboxylic acidHCID 69250314—
생성물(2S,4EZ)-N-(2,1,3-benzothiadiazol-4-yl)-4-(cyanomethylene)-1-(diphenylacetyl)-2-pyrrolidinecarboxamideHCID 69249372—

반응 단계

Following the general method as outlined in Example 22, startling from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(cyanomethylene)-2-pyrrolidinecarboxylic acid, diphenylacetyl chloride, and 2,1,3-benzothiadiazol-4-amine the title compound was obtained in 42% purity by LC/MS. MS(ESI+): m/z=480.4.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07211601B2
출처 데이터셋uspto-grants-2007_05
ORD IDord-128cffabf3f049ba8b3e80d302fe5d50
출처 메모uspto-grants-2007_05