Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,1,3-Benzothiadiazol-4-amine → (2S,4EZ)-N2-(2,1,3-benzothiadiazol-4-yl)-N1-(3,5-dichlorophenyl)-4-(methoxyimino)-1,2-pyrrolidinedicarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,1,3-Benzothiadiazol-4-amine | HCID 69845 | — |
| 반응물 | 3,5-Dichlorophenyl isocyanate | HCID 94460 | — |
| 반응물 | (2S,4EZ)-1(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid | HCID 58714586 | — |
| 생성물 | (2S,4EZ)-N2-(2,1,3-benzothiadiazol-4-yl)-N1-(3,5-dichlorophenyl)-4-(methoxyimino)-1,2-pyrrolidinedicarboxamide | HCID 131725485 | — |
반응 단계
Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid, 1,3-dichloro-5-isocyanatobenzene, and 2,1,3-benzothiadiazol-4-amine the title compound was obtained in 55% purity by LC/MS. MS(ESI+): m/z=479.6.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07211601B2 |
| 출처 데이터셋 | uspto-grants-2007_05 |
| ORD ID | ord-97e58fe4993846c4aa0037ba32d9c9c7 |
| 출처 메모 | uspto-grants-2007_05 |