2-Amino-6-fluorobenzylamine → HCID 178432155, 화합물
반응식
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([F:10])[C:3]=1[CH2:4][NH2:5].[CH2:11](C(CC)(CC)C([O-])([O-])[O-])[CH3:12]>C(O)C>[F:10][C:6]1[CH:7]=[CH:8][CH:9]=[C:2]2[C:3]=1[CH2:4][NH:5][C:11]([CH3:12])=[N:1]2참가 물질
4
실험 절차
A solution of 2-amino-6-fluorobenzylamine (1.1 g, 7.86 mmol) and triethylorthoacetate (1.58 mL, 8.64 mmol) in ethanol (30 mL) was heated at 80° C. for 14 h. The reaction mixture was allowed to cool to room temperature and evaporated in vacuo. The yellow oil was triturated with diethyl ether to give the title compound as white solid (0.74 g, 57%).
후처리
- customevaporated in vacuo
- customThe yellow oil was triturated with diethyl ether
출처 및 근거
- ORD 기록
- ord-f52556c8a9184fad8c10bd7d68a18e94
- 출처 데이터셋
- uspto-grants-2007_05
- 특허 번호
- US07214674B2
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