2-Chloroaniline → N-(2-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrrol-2-yl)-2-(2-oxo-1,2-dihydroindol-3-ylidene)-acetamide

HRID 1350183노트

반응식

HRID 1350183 반응식
[CH3:1][C:2]1[CH:6]=[C:5]([CH3:7])[NH:4][C:3]=1[C:8](=[C:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[NH:14][C:13]1=[O:21])[C:9](O)=[O:10].[Cl:22][C:23]1[CH:29]=[CH:28][CH:27]=[CH:26][C:24]=1[NH2:25]>>[Cl:22][C:23]1[CH:29]=[CH:28][CH:27]=[CH:26][C:24]=1[NH:25][C:9](=[O:10])[C:8]([C:3]1[NH:4][C:5]([CH3:7])=[CH:6][C:2]=1[CH3:1])=[C:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[NH:14][C:13]1=[O:21]

참가 물질

3

반응물 2

HCID 72402-ChloroanilineHCID 69453471HCID 69453471, 화합물

생성물 1

HCID 69507446N-(2-Chlorophenyl)-2-(3,5-dimethyl-1H-pyrrol-2-yl)-2-(2-oxo-1,2-dihydroindol-3-ylidene)-acetamide수율 22.4%

실험 절차

(3,5-Dimethyl-1H-pyrrol-2-yl)-(2-oxo-1,2-dihydro-indol-3-ylidene)-acetic acid (90 mg) was reacted with 2-chloroaniline (80 mg) using method B to give 28 mg (22%) of the title compound.

출처 및 근거

ORD 기록
ord-20ce9cde82c0411ea5f6482163323be2
출처 데이터셋
uspto-grants-2007_05
특허 번호
US07214700B2

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