Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 1-Carbomethoxy-2-benzylamino-3,4-dihydronaphthalene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Isobutyric Acid | HCID 6590 | — |
| 반응물 | Benzylamine | HCID 7504 | — |
| 반응물 | 1-Naphthalenecarboxylic acid, 1,2,3,4-tetrahydro-2-oxo-, methyl ester | HCID 599131 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 1-Carbomethoxy-2-benzylamino-3,4-dihydronaphthalene | HCID 21094673 | 102.4% |
반응 단계
To a solution of 1-carbomethoxy-2-oxo-1,2,3,4-tetrahydronaphthalene (10.2 g) and isobutyric acid (4.84 g) in toluene (150 mL) stirring at room temperature under argon, was added benzylamine (5.35 g). The resulting mixture was heated to reflux for 2 h with water removal using a Dean-Stark trap. The solvent was then evaporated under vacuum to provide the title compound (15 g) as a yellow gum.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07214704B2 |
| 출처 데이터셋 | uspto-grants-2007_05 |
| ORD ID | ord-e1562b7a1b0342efa5869dca9cb48120 |
| 출처 메모 | uspto-grants-2007_05 |