Ethyl 2-(4-bromophenyl)-2-methylpropanoate → 2-Methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)phenyl)propanoic acid

반응식

[CH3:1][C:2]([C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][N:16]=2)=[CH:11][CH:10]=1)([CH3:8])[C:3]([O:5]CC)=[O:4].BrC1C=CC(C(C)(C)C(OCC)=O)=CC=1>>[CH3:8][C:2]([C:9]1[CH:10]=[CH:11][C:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:23])([F:24])[F:22])=[CH:17][N:16]=2)=[CH:13][CH:14]=1)([CH3:1])[C:3]([OH:5])=[O:4]

참가 물질

반응물 2

HCID 11277257Ethyl 2-(4-bromophenyl)-2-methylpropanoate

HCID 21099802Ethyl 2-methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)phenyl)propanoate

생성물 1

HCID 210997162-Methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)phenyl)propanoic acid

실험 절차

The title compound was prepared according to the method of Example 22B, substituting the product of Example 26B for the product of Example 22A.

출처 및 근거

ORD 기록: ord-120c35429571435aa9d3e915e25a1d72
출처 데이터셋: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07217838B2

반응 노트

불러오는 중…