10-Methoxyibogamine → CID 44359441

HRID 1352187

반응식

HRID 1352187 반응식
[CH3:1][CH2:2][C@@H:3]1[C@@H:8]2[N:9]3[CH2:11][CH2:12][C:13]4[C:17]5[CH:18]=[C:19]([O:22]C)[CH:20]=[CH:21][C:16]=5[NH:15][C:14]=4[C@@H:7]2[CH2:6][C@@H:5]([CH2:10]3)[CH2:4]1.B(Br)(Br)Br.C(Cl)Cl>>[CH3:1][CH2:2][C@H:3]1[CH:8]2[N:9]3[CH2:11][CH2:12][C:13]4[C:17]5[CH:18]=[C:19]([OH:22])[CH:20]=[CH:21][C:16]=5[NH:15][C:14]=4[C@H:7]2[CH2:6][CH:5]([CH2:10]3)[CH2:4]1

참가 물질

3

반응물 2

HCID 44210810-Methoxyibogamine2회HCID 22277759Boron tribromide dichloromethane

생성물 1

HCID 44359441CID 44359441

실험 절차

Noribogaine is synthesized by the O-demethylation of ibogaine. This may be accomplished, for example, by reacting ibogaine with boron tribromide/methylene chloride at room temperature and then purifying the product using known procedures. At present, noribogaine may also be obtained from the National Institute on Drug Abuse (Rockville, Md.). The compound has the following structure:

후처리

  1. customat room temperature
  2. custompurifying the product

출처 및 근거

ORD 기록
ord-c915d17f15e7494d9314ddada26f95d1
출처 데이터셋
uspto-grants-2007_05
특허 번호
US07220737B1

연결된 노트

불러오는 중…