참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | N,N-Dimethylaniline | HCID 949 | — |
| 반응물 | Propofol | HCID 4943 | — |
| 반응물 | Phosgene | HCID 6371 | — |
| 생성물 | 2,6-Di(propan-2-yl)phenyl carbonochloridate | HCID 271619 | — |
반응 단계
Phosgene (13 mL, 20% in toluene) was added to propofol (3.6 g, 20 mmol) under a nitrogen atmosphere. The mixture was cooled to 0° C. and N,N-dimethylaniline (3.3 mL, 26 mmol) was added dropwise. The reaction mixture was allowed to warm to room temperature slowly and stirred for 14 h. The solvent was removed in vacuo. The crude product was carried to next step without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07220875B2 |
|---|
| 출처 데이터셋 | uspto-grants-2007_05 |
|---|
| ORD ID | ord-3a3bb6e61312458e836096027f049d39 |
|---|
| 출처 메모 | uspto-grants-2007_05 |
|---|
