Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(4-Chlorophenyl)(phenyl)methanamine → (2S)-3-[4-({[(4-chloro-phenyl)-phenyl-methyl]-carbamoyl}-methoxy)-phenyl]-2-methoxy-propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (4-Chlorophenyl)(phenyl)methanamine | HCID 409810 | — |
| 반응물 | (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)propionic acid | HCID 9847886 | — |
| 반응물 | (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester | HCID 58864673 | — |
| 생성물 | (2S)-3-[4-({[(4-chloro-phenyl)-phenyl-methyl]-carbamoyl}-methoxy)-phenyl]-2-methoxy-propionic acid | HCID 58646617 | — |
반응 단계
The title compound was prepared from (2S)-3-(4-carboxymethoxy-phenyl)-2-methoxy-propionic acid ethyl ester (PREPARATION 3, step 2) and C-(4-chloro-phenyl)-C-phenyl-methylamine via the same procedure used for the preparation of (2S,1R)-2-ethoxy-3-(4-{1-[2-(4-phenoxy-phenyl)-ethylcarbamoyl]-ethoxy}-phenyl)-propionic acid (Example 1, step 3) to produce a yellow oil. MS (ES) for C25H24ClNO5 [M+H]+: 454.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07220880B2 |
| 출처 데이터셋 | uspto-grants-2007_05 |
| ORD ID | ord-ce42f56585c04bc78d511f350faee07a |
| 출처 메모 | uspto-grants-2007_05 |