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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1354758생성일: 2026년 10월 27일

Acetone → tert-Butyl (R)-[1-(2-fluoro-4-isopropylaminophenyl)pyrrolidin-3-yl]methylcarbamate

https://huagongshe.com/reaction/1354758

반응식

참여 물질

역할이름HCID투입량
반응물AcetoneHCID 180—
반응물TriacetoxyborohydrideHCID 2724942—
반응물tert-Butyl (R)-[1-(4-amino-2-fluorophenyl)pyrrolidin-3-yl]methylcarbamateHCID 68988249—
생성물tert-Butyl (R)-[1-(2-fluoro-4-isopropylaminophenyl)pyrrolidin-3-yl]methylcarbamateHCID 86594881—

반응 단계

tert-Butyl (R)-[1-(4-amino-2-fluorophenyl)pyrrolidin-3-yl]methylcarbamate was alkylated with acetone using triacetoxyborohydride as reducing agent by method N. This resulted in the product with the molecular weight of 351.47 (C19H30FN3O2); MS (ESI): 352 (M+H+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07223788B2
출처 데이터셋uspto-grants-2007_05
ORD IDord-2cd95b45e15e4e1387e3f728178a8533
출처 메모uspto-grants-2007_05