Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(Benzenesulfonyl)-3-phenyloxaziridine → 2-(Methylsulfinyl)pyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(Benzenesulfonyl)-3-phenyloxaziridine | HCID 320405 | — |
| 반응물 | 2-(Methylsulfanyl)pyrimidine | HCID 522772 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-(Methylsulfinyl)pyrimidine | HCID 11400832 | — |
반응 단계
The methylsulfanyl-pyrimidine compound of formula (83) is reacted with an oxidising agent, preferably 3-phenyl-2-(phenylsulfonyl)oxaziridine, in an organic solvent, preferably dichloromethane, at room temperature. The product of formula (84), a methanesulfinyl-pyrimidine derivative, is isolated by conventional means, and preferably reacted in the next step without further purification. The product of formula (84) may, however, be additionally purified by means of chromatography or recrystallisation.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06586441B2 |
| 출처 데이터셋 | uspto-grants-2003_07 |
| ORD ID | ord-224b15c6ee9741c48c8a184c2ab8484f |
| 출처 메모 | uspto-grants-2003_07 |