1,8-Diazabicyclo(5.4.0)undec-7-ene → 2-Amino-4-furan-2-yl-6-[(quinolin-2-ylmethyl)-amino]-pyrimidine-5-carbonitrile

HRID 1355968

반응식

HRID 1355968 반응식
[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4](S(C)=O)[N:3]=1.Cl.Cl.[NH2:20][CH2:21][C:22]1[CH:31]=[CH:30][C:29]2[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=2)[N:23]=1.C1CCN2C(=NCCC2)CC1>COCCOC>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH:10]=[CH:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4]([NH:20][CH2:21][C:22]2[CH:31]=[CH:30][C:29]3[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=3)[N:23]=2)[N:3]=1

참가 물질

5

반응물 3

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507294(Quinolin-2-yl)methanamine dihydrochlorideHCID 185076922-Amino-4-(furan-2-YL)-6-(methylsulfinyl)pyrimidine-5-carbonitrile

생성물 1

HCID 101321522-Amino-4-furan-2-yl-6-[(quinolin-2-ylmethyl)-amino]-pyrimidine-5-carbonitrile

시약·촉매·용매 1

HCID 80711,2-Dimethoxyethane용매

실험 절차

From 2-amino-4-furan-2-yl-6-methanesulfinyl-pyrimidine-5-carbonitrile, 2-aminomethyl-quinoline dihydrochloride and DBU in DME. ES-MS m/e (%): 343 (M+H+, 100).

출처 및 근거

ORD 기록
ord-8d698abf96a248b7bc6cd648b1a9e3cc
출처 데이터셋
uspto-grants-2003_07
특허 번호
US06586441B2

연결된 노트

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