Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 2-Amino-4-(3-fluoro-phenyl)-6-methylsulfanyl-pyrimidine-5-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Fluorophenylboronic acid | HCID 2733986 | — |
| 반응물 | 2-Amino-4-chloro-6-methylsulfanyl-pyrimidine-5-carbonitrile | HCID 18507260 | — |
| 촉매 | Tetrakis(triphenylphosphine)palladium | HCID 11979704 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2-Amino-4-(3-fluoro-phenyl)-6-methylsulfanyl-pyrimidine-5-carbonitrile | HCID 18507679 | — |
반응 단계
From 2-amino-4-chloro-6-methylsulfanyl-pyrimidine-5-carbonitrile, m-fluorobenzeneboronic acid, tetrakis(triphenylphosphine)palladium(O) and potassium carbonate in toluene. EI-MS m/e (%): 260 (M+, 40), 259 ([M—H]+, 100).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06586441B2 |
| 출처 데이터셋 | uspto-grants-2003_07 |
| ORD ID | ord-d2230b2a704e403d8e597ab060ee818d |
| 출처 메모 | uspto-grants-2003_07 |