Cesium carbonate → 2-Amino-4-(4,5-dihydro-furan-2-yl)-6-(pyridin-2-yl-methoxy)-pyrimidine-5-carbonitrile
반응식
[NH2:1][C:2]1[NH:3][C:4](=[O:15])[C:5]([C:13]#[N:14])=[C:6]([C:8]2[O:9][CH2:10][CH2:11][CH:12]=2)[N:7]=1.Cl.[N:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[CH2:23]Cl.C(=O)([O-])[O-].[Cs+].[Cs+]>CN(C=O)C>[NH2:1][C:2]1[N:7]=[C:6]([C:8]2[O:9][CH2:10][CH2:11][CH:12]=2)[C:5]([C:13]#[N:14])=[C:4]([O:15][CH2:23][C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][N:17]=2)[N:3]=1참가 물질
5
반응물 3
생성물 1
시약·촉매·용매 1
실험 절차
From 2-amino-4-(4,5-dihydro-furan-2-yl)-6-oxo-1,6-dihydro-pyrimidine-5-carbonitrile, 2-picolyl chloride hydrochloride and caesium carbonate in DMF. ES-MS m/e (%): 296 (M+H+, 100).
출처 및 근거
- ORD 기록
- ord-38c2b32f1187499fa6728dafcfcee7be
- 출처 데이터셋
- uspto-grants-2003_07
- 특허 번호
- US06586441B2
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