돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1356161생성일: 2026년 10월 27일

1,8-Diazabicyclo(5.4.0)undec-7-ene → 2-Amino-4-pyrazol-1-yl-6-[(quinolin-2-yl-methyl)-amino]-pyrimidine-5-carbonitrile

https://huagongshe.com/reaction/1356161

반응식

참여 물질

역할이름HCID투입량
반응물1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
반응물2-Amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrileHCID 18507520—
반응물Quinolin-2-ylmethanamine hydrochlorideHCID 18507529—
용매1,2-DimethoxyethaneHCID 8071—
생성물2-Amino-4-pyrazol-1-yl-6-[(quinolin-2-yl-methyl)-amino]-pyrimidine-5-carbonitrileHCID 18507579—

반응 단계

From 2-amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrile, C-quinolin-2-yl-methylamine hydrochloride and DBU in DME. ES-MS m/e (%): 343 (M+H+, 100).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06586441B2
출처 데이터셋uspto-grants-2003_07
ORD IDord-4fa9b08c5edb4ffe80d7b6ecb60e176c
출처 메모uspto-grants-2003_07