Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,8-Diazabicyclo(5.4.0)undec-7-ene → 2-Amino-4-(isoquinolin-3-yl-methoxy)-6-pyrazol-1-yl-pyrimidine-5-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| 반응물 | Isoquinolin-3-ylmethanol | HCID 12874869 | — |
| 반응물 | 2-Amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrile | HCID 18507520 | — |
| 용매 | 1,2-Dimethoxyethane | HCID 8071 | — |
| 생성물 | 2-Amino-4-(isoquinolin-3-yl-methoxy)-6-pyrazol-1-yl-pyrimidine-5-carbonitrile | HCID 18507667 | — |
반응 단계
From 2-amino-4-methanesulfinyl-6-pyrazol-1-yl-pyrimidine-5-carbonitrile, isoquinolin-3-yl-methanol and DBU in DME. ES-MS m/e (%): 366 (M+Na+, 60), 344 (M+H+, 100).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06586441B2 |
| 출처 데이터셋 | uspto-grants-2003_07 |
| ORD ID | ord-923d9552297144629b5295ff5ebc272a |
| 출처 메모 | uspto-grants-2003_07 |