Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(4-Nitrophenyl)-1H-imidazole → 4-(1H-imidazol-1-yl)aniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(4-Nitrophenyl)-1H-imidazole | HCID 123155 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 4-(1H-imidazol-1-yl)aniline | HCID 320165 | 89% |
반응 단계
1-(4-nitrophenyl)-1H-imidazole (4.4 g; 23.5 mmoles) is put in solution in anhydrous methanol (140 ml) and palladium on carbon (0.44 g) is added to the medium. The reaction medium is placed under hydrogen for 4 hours. The catalyst is filtered off and the solvent is evapored to dryness. The expected product is obtained in a virtually pure state with a yield of 89% (3.3 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06586454B2 |
| 출처 데이터셋 | uspto-grants-2003_07 |
| ORD ID | ord-d3b5d2b3792c43ce82a9fa60ed0a9925 |
| 출처 메모 | uspto-grants-2003_07 |