4-(3-(Dimethylamino)propoxy)aniline → HCID 18186454, 화합물
반응식
[Br:1][C:2]1[C:3]([NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([CH3:16])[N:11]=2)=[N:4][C:5](Cl)=[N:6][CH:7]=1.[CH3:17][N:18]([CH2:20][CH2:21][CH2:22][O:23][C:24]1[CH:30]=[CH:29][C:27]([NH2:28])=[CH:26][CH:25]=1)[CH3:19]>>[Br:1][C:2]1[C:3]([NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([CH3:16])[N:11]=2)=[N:4][C:5]([NH:28][C:27]2[CH:26]=[CH:25][C:24]([O:23][CH2:22][CH2:21][CH2:20][N:18]([CH3:17])[CH3:19])=[CH:30][CH:29]=2)=[N:6][CH:7]=1참가 물질
3
실험 절차
Using an analogous method to that described in Example 136, but starting from 5-bromo-2-chloro-4-[(6-methylpyrid-2-yl)amino]pyrimidine (Method 84) and 4-[3-(N,N-dimethylamino)propoxy]aniline (obtained as described in WO 9909030), the product was obtained. MS (MH+): 457, 459; HPLC (RT): 5.26.
후처리
- customthe product was obtained
- customHPLC (RT)
출처 및 근거
- ORD 기록
- ord-47db18c47b9c4270a785ba85ed817594
- 출처 데이터셋
- uspto-grants-2003_07