2-Chloro-6-(1-piperazinyl)pyrazine → 2-[(3-Cyanobenzyl)Oxy]-6-(1-Piperazinyl)Pyrazine

HRID 1357629

반응식

HRID 1357629 반응식
Cl[C:2]1[CH:7]=[N:6][CH:5]=[C:4]([N:8]2[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]2)[N:3]=1.[C:14]([C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=1)[CH2:19][OH:20])#[N:15]>>[C:14]([C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][CH:23]=1)[CH2:19][O:20][C:2]1[CH:7]=[N:6][CH:5]=[C:4]([N:8]2[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]2)[N:3]=1)#[N:15]

참가 물질

3

반응물 2

HCID 1079922-Chloro-6-(1-piperazinyl)pyrazineHCID 27346773-(Hydroxymethyl)benzonitrile

생성물 1

HCID 98573352-[(3-Cyanobenzyl)Oxy]-6-(1-Piperazinyl)Pyrazine

실험 절차

Starting materials, 2-chloro-6-(1-piperazinyl)pyrazine and 3-cyanobenzyl alcohol. Fragmenting mass analysis supports the stated structure. Purity 90% (HPLC). HRMS m/z calcd for C16H17N5O (M)+ 295.1433, found 295.1431.

출처 및 근거

ORD 기록
ord-f50648e036494137895431dab2867622
출처 데이터셋
uspto-grants-2003_07
특허 번호
US06593330B2

연결된 노트

불러오는 중…