Nitric Acid → HCID 54161804, 화합물

HRID 1357856

반응식

HRID 1357856 반응식
[C:1]1([C@H:7]([CH3:12])[CH2:8][C:9]([OH:11])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(=O)(=O)(O)O.[N+:18]([O-])([OH:20])=[O:19]>O>[N+:18]([C:4]1[CH:5]=[CH:6][C:1]([C@H:7]([CH3:12])[CH2:8][C:9]([OH:11])=[O:10])=[CH:2][CH:3]=1)([O-:20])=[O:19]

참가 물질

5

반응물 3

HCID 944Nitric AcidHCID 1118Sulfuric AcidHCID 852992(3R)-3-phenylbutanoic acid

생성물 1

HCID 54161804HCID 54161804, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

(R)-3-phenylbutanoic acid (10.0 g) was added to concentrated sulphuric acid (40 mL) at −5° C. under nitrogen. The resulting thick gel-like mixture was stirred vigorously and fuming nitric acid (2.8 mL) was added slowly over 20 minutes. The reaction mixture was poured onto a mixture of ice and water (500 mL) and the resulting white precipitate was collected by filtration, then washed thoroughly with water, and then dried to give the title compound (10.1 g) as a white solid.

후처리

  1. filtrationthe resulting white precipitate was collected by filtration
  2. washwashed thoroughly with water
  3. customdried

출처 및 근거

ORD 기록
ord-9f4a8f80140440f19ca0f2accf3509d4
출처 데이터셋
uspto-grants-2003_07
특허 번호
US06593354B2

연결된 노트

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