참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Sodium Azide | HCID 33557 | — |
| 반응물 | 4-Fluorobenzaldehyde | HCID 68023 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 4-Azidobenzaldehyde | HCID 90385 | — |
반응 단계
50 g 4-fluoro benzaldehyde and 50 g sodium azide were dispersed in 150 ml dry dimethyl sulfoxide. Subsequently, the mixture was heated for 3 hours at 105° C. while nitrogen was introduced. The mixture was poured into 200 ml water, and the solution extracted with 200 ml dichloro methane (three times). Then the solvent was distilled off by means of a vacuum rotation vaporizer. 53 g of a liquid remained having infrared (IR) and nuclear magnetic resonance (NMR) spectra consistent with the 4-azido benzaldehyde structure.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06596460B2 |
|---|
| 출처 데이터셋 | uspto-grants-2003_07 |
|---|
| ORD ID | ord-83d9711f65f642a6b84fcbd04a7e823b |
|---|
| 출처 메모 | uspto-grants-2003_07 |
|---|
