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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1358272생성일: 2026년 10월 27일

7-Amino-4-(3-bromoanilino)-6-nitroquinazoline → N4-(3-bromophenyl)-4,6,7-Quinazolinetriamine

https://huagongshe.com/reaction/1358272

반응식

참여 물질

역할이름HCID투입량
반응물7-Amino-4-(3-bromoanilino)-6-nitroquinazolineHCID 5328214—
촉매IronHCID 23925—
용매EthanolHCID 702—
생성물N4-(3-bromophenyl)-4,6,7-QuinazolinetriamineHCID 242665%

반응 단계

Iron dust reduction of 7-amino-4-(3-bromoanilino)-6-nitroquinazoline (0.5 g, 1.4 mmol) in 65% aqueous EtOH containing sufficient aqueous HCl to ensure solubility gives 4-(3-bromoanilino)-6,7-diaminoquinazoline (0.30 g, 65%). 1H NMR (DMSO) δ9.14 (1H, s), 8.27 (1H, s), 8.23 (1H, brs), 7.85 (1H, d, J=8.0 Hz), 7.31-7.14 (2H, m), 7.29 (1H, s), 6.79 (1H, s), 5.73 (2H, brs), 5.13 (2H, brs).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06596726B1
출처 데이터셋uspto-grants-2003_07
ORD IDord-0d1fb1785bee4cb3b05ddf7d05af90da
출처 메모uspto-grants-2003_07