Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N4-(3-bromophenyl)-4,6,7-Quinazolinetriamine → N-(3-bromophenyl)pyrazino[2,3-g]quinazolin-4-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N4-(3-bromophenyl)-4,6,7-Quinazolinetriamine | HCID 2426 | — |
| 반응물 | 1,4-Dioxane-2,3-diol | HCID 96170 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | N-(3-bromophenyl)pyrazino[2,3-g]quinazolin-4-amine | HCID 5328246 | 84.1% |
반응 단계
A mixture of 4-(3-bromoanilino)-6,7-diaminoquinazoline (90 mg, 0.27 mmol) and 1,4-dioxane-2,3-diol (0.2 g, 1.6 mmol) [Venuti, M. C.; Synthesis, 1982, 61-63] in MeOH (20 mL) is stirred at room temperature overnight to give a precipitate of 4-(3-bromoanilino)pyrazino[2,3-g]quinazoline (80 mg, 83%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06596726B1 |
| 출처 데이터셋 | uspto-grants-2003_07 |
| ORD ID | ord-9bc38be78ea04612aa042065386db123 |
| 출처 메모 | uspto-grants-2003_07 |