Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanolamine → 5-methyl-N-[6-(2-aminoethoxy)-5-(o-methoxyphenoxy)-2-(4-pyridyl)-4-pyrimidinyl]-2-pyridine sulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanolamine | HCID 700 | — |
| 반응물 | HCID 11202530 | HCID 11202530 | — |
| 생성물 | 5-methyl-N-[6-(2-aminoethoxy)-5-(o-methoxyphenoxy)-2-(4-pyridyl)-4-pyrimidinyl]-2-pyridine sulfonamide | HCID 18184254 | — |
반응 단계
According to the procedure described in Example 4b) 1.0 g 5-methyl-N-[6-chloro-5-(o-methoxyphenoxy)-2-(4-pyridyl)-4-pyrimidinyl]-2-pyridine sulfonamide was reacted with 2-aminoethanol to give 950 mg 5-methyl-N-[6-(2-aminoethoxy)-5-(o-methoxyphenoxy)-2-(4-pyridyl)-4-pyrmidinyl]-2-pyridine sulfonamide. LC-MS: tR=3.00 min, (M+1]+=509.53, [M−1]−=507.57.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06596719B1 |
| 출처 데이터셋 | uspto-grants-2003_07 |
| ORD ID | ord-59374a89cbf542d0809acb294d6dd1b5 |
| 출처 메모 | uspto-grants-2003_07 |