Ethanol → HCID 9855924, 화합물

HRID 1358543노트

반응식

HRID 1358543 반응식
[C:1]([C:4]1[CH2:5][CH2:6][O:7][C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[CH:10]=1)([OH:3])=[O:2].[CH2:15](O)[CH3:16]>S(=O)(=O)(O)O>[CH2:15]([O:2][C:1]([C:4]1[CH2:5][CH2:6][O:7][C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[CH:10]=1)=[O:3])[CH3:16]

참가 물질

4

반응물 2

HCID 702EthanolHCID 11116823HCID 11116823, 화합물

생성물 1

HCID 9855924HCID 9855924, 화합물

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매

실험 절차

A mixture of 8.2 g (0.043 mol) of 2,3-dihydro-4-carboxybenzoxepine in 150 ml of ethanol and 5 ml of concentrated sulphuric acid is brought to reflux for 6 hours. The reaction mixture is subsequently concentrated under reduced pressure and the residue is taken up in water. The combined mixture is extracted with ethyl acetate. The organic phase is then washed with sodium bicarbonate and then with water and dried over anhydrous sodium sulphate before being concentrated under reduced pressure. 8.5 g of an orange oil are thus obtained.

후처리

  1. temperatureto reflux for 6 hours
  2. concentrationThe reaction mixture is subsequently concentrated under reduced pressure
  3. extractionThe combined mixture is extracted with ethyl acetate
  4. washThe organic phase is then washed with sodium bicarbonate
  5. dry with materialwith water and dried over anhydrous sodium sulphate
  6. concentrationbefore being concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-f478c6f1b4a94736b09a56fd719e7e3a
출처 데이터셋
uspto-grants-2003_07
특허 번호
US06596758B1

반응 노트

불러오는 중…