Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → 3-(2-Methylphenyl)propanoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | 3-(2-Methylphenyl)propionic acid | HCID 30938 | — |
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3-(2-Methylphenyl)propanoyl chloride | HCID 13029201 | — |
반응 단계
A mixture of 2-methylhydrocinnamic acid (3.0 g, 18.3 mmole), oxalyl chloride (3.19 ml, 36.6 mmole) and methylene chloride (30 ml) was cooled in an ice bath and N,N-dimethylformamide (0.14 ml, 1.81 mmole) was added dropwise. The mixture was stirred at room temperature overnight. Concentration in vacuo gave 3-(2-methylphenyl)propanoyl chloride which was taken up in methylene chloride and used in the next step as a crude.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06600015B2 |
| 출처 데이터셋 | uspto-grants-2003_07 |
| ORD ID | ord-e73ff8e2d55a4b51a053c53a0659d534 |
| 출처 메모 | uspto-grants-2003_07 |