Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 4-[2-(2-Chloromethyl-phenoxy)-ethyl]-morpholine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | [2-(2-Morpholinoethoxy)phenyl]methanol | HCID 7164615 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-[2-(2-Chloromethyl-phenoxy)-ethyl]-morpholine hydrochloride | HCID 18179952 | — |
반응 단계
Thionyl chloride (5 mL, 2M in DCM) was added to a solution of [2-(2-morpholin-4-yl-ethoxy)-phenyl]-methanol (1.97 g, 8.3 mmol) in DCM (15 mL) at 0° C. The mixture was allowed to warm up to rt and stirred for 3 hours. The reaction was concentrated to give 4-[2-(2-chloromethyl-phenoxy)-ethyl]-morpholine hydrochloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06599902B2 |
| 출처 데이터셋 | uspto-grants-2003_07 |
| ORD ID | ord-be00cb7769404c78a5a43fa97f876643 |
| 출처 메모 | uspto-grants-2003_07 |